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  • Name: Carbohydrate Analysis Media
  • Id: AG001

Ligand exchange is the preferred method for the chromatographic analysis and separation of many sugars and sugar alcohols due to the advantage of simply using water as eluent. In ligand exchange, the negatively charged hydroxy groups in carbohydrate molecules interact with the positively charged metal containing groups on the chromatography substrates. The carbohydrates are eluted by polar water mobile phase.


Nano-Micro has developed a complete line of high performance chromatographic media for the analysis and separation of carbohydrates. The media are prepared by sulfonating poly(styrene-co-divinylbenzene) microspheres followed by chelating of various metal ions such as calcium (Ca2+) and sodium (Na+).


Nano-Micro’s high performance analysis resins provide high resolution and high efficiency separation of carbohydrates, alcohols and organic acids because of their precisely controlled particle size and extremely narrow particle size distribution. The particle size can be selected from 5, 6, 8, 10, 20, and 100 μm with cross-linking degree at 5%, 8%, or 10%. These high stable resins provide high resolution, low back pressure, and reliable lot-to-lot reproducibility.


Cationic resin for the analysis and separation of carbohydrate and organic acid


SEM pictures of poly(styrene-co-divinylbenzene) microspheres


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