NMCHT Type I/ NMCHT Type II

Product Ordering
  • Product description
  • Characteristics
  • Documents
  • Ordering Information

Ceramic hydroxyapatite (CHT) is a hydroxyapatite-based composite material with important application value as a chromatographic media. It has a spherical appearance and macropores. Unlike traditional chromatographic media, CHT is a mixed-mode resin with both metal affinity and cation ion exchange capabilities offers a unique selectivity that can provide unique and effective purification solutions. CHT chromatography media can be used for the purification of various types of biomacromolecules, including: antibodies, virus particles, vaccines, recombinant proteins and nucleic acid, etc.

NMCHT Type I has a higher binding capacity and is suitable for small protein purification. NMCHT Type II has a larger pore size and is more suitable for the purification of macromolecules such as viruses, IgM, VLP particles, plasmids, etc.


Product name

NMCHT Type I

NMCHT Type II

Functional group

Ca2+, PO43-, -OH

Particle size

40±4 μm

Tap-settled density

0.72 g/ml

DBC(IgG)

~35 mg/ml

~15 mg/ml

Recommended flow rate

50-1000 cm/h

Sanitization

1-2 M NaOH

pH stability

6.5-14, at least 1year in 1 M NaOH

Regeneration

0.4 M sodium phosphate buffer,pH 7-7.5;

1 M trisodium phosphate,pH 11-12;

If a higher phosphate concentration is required, please use 0.4-1 M potassium phosphate buffer

Autoclavability

121 ℃,20 min, phosphate buffer, pH 7.

Storage*

0.1 M NaOH, room temperature

* Please store the product under sealed, room temperature(2-30℃), and dry conditions in original packaging. Here are the recommended storage conditions once the package has been opened.


Product name

Package

Cat. No.

NMCHT Type I

10 g

80000-040001-4010

100 g

80000-040001-4100

1 KG

80000-040001-3001

5 KG

80000-040001-3005

NMCHT Type II

10 g

80000-040002-4010

100 g

80000-040002-4100

1 KG

80000-040002-3001

5 KG

80000-040002-3005