NanoGel series IEX resins are designed for purification of large modality biologics such as antibodies , viral vectors and vaccines. Their supports are rigid poly(styrene-divinylbenzene) (PS-DVB) beads of uniformed particle size and very large pores (average pore size ≥ 1500 Å). Through polyhydroxyl surface modification and special surface extender chemistry, these NanoGel ion exchange resins are enabled with low non-specific binding property and high binding capacity.
Excellent Pressure-Flow Characteristics
High mass transfer and high binding capacity for large biomolecules
Salt-tolerance
Product Name | NanoGel™-50Q HC | NanoGel™-50Q | NanoGel™-50SP | NanoGel™-50SP HP |
Chromatography Technique | Strong anion | Strong anion | Strong cation | Strong cation |
Matrix | PS/DVB | PS/DVB | PS/DVB | PS/DVB |
Particle Size | 50 μm | 50 μm | 50 μm | 50 μm |
Ligand | Quaternary ammonium | Quaternary ammonium | Sulfonate | Sulfonate |
Ligand Density | ~0.25 meq·mL-1 | ~0.20 meq·mL-1 | ~0.16 meq·mL-1 | ~0.14 meq·mL-1 |
Dynamic Binding Capacity | ~120 mg·mL-1(BSA) | ~80 mg·mL-1(BSA) | ~100 mg·mL-1(Lys) | ~70 mg·mL-1(hIgG) |
Maximum Pressure | 2.0 MPa | 2.0 MPa | 2.0 MPa | 2.0 MPa |
Clean In Place | 1 M NaOH | 1 M NaOH | 1 M NaOH | 1 M NaOH |
Recommended Flow Velocity | 300-1200 cm/h | |||
pH Stability | 1-14 | |||
Chemical Stability | Stable in commonly used buffers, 1 M HAc, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropyl alcohol, 30% acetonitrile,1% SDS, 6 M guanidine hydrochloride, 8 M urea, etc. Avoid long-term exposure to strong oxidant. | |||
Operational Temperature | 4-30 ℃ | |||
Storage | 20% Ethanol, 4-25 ℃ |
Product Name | Pack Size | Cat. No. |
NanoGel-50SP 10mL | 10mL | 04062-050200-2010 |
NanoGel-50SP 30mL | 30mL | 04062-050200-2030 |
NanoGel-50SP 50mL | 50mL | 04062-050200-2050 |
NanoGel-50SP 100mL | 100mL | 04062-050200-2100 |
NanoGel-50SP 300mL | 300mL | 04062-050200-2300 |
NanoGel-50SP 500mL | 500mL | 04062-050200-2500 |
NanoGel-50SP 1L | 1L | 04062-050200-1001 |
NanoGel-50SP 5L | 5L | 04062-050200-1005 |
NanoGel-50SP 10L | 10L | 04062-050200-1010 |
NanoGel-50SP 50L | 50L | 04062-050200-1050 |
NanoGel-50SP 100L | 100L | 04062-050200-1100 |
NanoGel-50SP HP 10mL | 10mL | 04062-050150-2010 |
NanoGel-50SP HP 30mL | 30mL | 04062-050150-2030 |
NanoGel-50SP HP 50mL | 50mL | 04062-050150-2050 |
NanoGel-50SP HP 100mL | 100mL | 04062-050150-2100 |
NanoGel-50SP HP 300mL | 300mL | 04062-050150-2300 |
NanoGel-50SP HP 500mL | 500mL | 04062-050150-2500 |
NanoGel-50SP HP 1L | 1L | 04062-050150-1001 |
NanoGel-50SP HP 5L | 5L | 04062-050150-1005 |
NanoGel-50SP HP 10L | 10L | 04062-050150-1010 |
NanoGel-50SP HP 50L | 50L | 04062-050150-1050 |
NanoGel-50SP HP 100L | 100L | 04062-050150-1100 |
NanoGel-50Q 10mL | 10mL | 04064-050200-2010 |
NanoGel-50Q 30mL | 30mL | 04064-050200-2030 |
NanoGel-50Q 50mL | 50mL | 04064-050200-2050 |
NanoGel-50Q 100mL | 100mL | 04064-050200-2100 |
NanoGel-50Q 300mL | 300mL | 04064-050200-2300 |
NanoGel-50Q 500mL | 500mL | 04064-050200-2500 |
NanoGel-50Q 1L | 1L | 04064-050200-1001 |
NanoGel-50Q 5L | 5L | 04064-050200-1005 |
NanoGel-50Q 10L | 10L | 04064-050200-1010 |
NanoGel-50Q 50L | 50L | 04064-050200-1050 |
NanoGel-50Q 100L | 100L | 04064-050200-1100 |
NanoGel-50Q HC 10mL | 10mL | 04064-050150-2010 |
NanoGel-50Q HC 30mL | 30mL | 04064-050150-2030 |
NanoGel-50Q HC 50mL | 50mL | 04064-050150-2050 |
NanoGel-50Q HC 100mL | 100mL | 04064-050150-2100 |
NanoGel-50Q HC 300mL | 300mL | 04064-050150-2300 |
NanoGel-50Q HC 500mL | 500mL | 04064-050150-2500 |
NanoGel-50Q HC 1L | 1L | 04064-050150-1001 |
NanoGel-50Q HC 5L | 5L | 04064-050150-1005 |
NanoGel-50Q HC 10L | 10L | 04064-050150-1010 |
NanoGel-50Q HC 50L | 50L | 04064-050150-1050 |
NanoGel-50Q HC 100L | 100L | 04064-050150-1100 |