NanoGel series IEX resins are designed for purification of large modality biologics such as antibodies , viral vectors and vaccines. Their supports are rigid poly(styrene-divinylbenzene) (PS-DVB) beads of uniformed particle size and very large pores (average pore size ≥ 1500 Å). Through polyhydroxyl surface modification and special surface extender chemistry, these NanoGel ion exchange resins are enabled with low non-specific binding property and high binding capacity.
Excellent Pressure-Flow Characteristics
High mass transfer and high binding capacity for large biomolecules
Salt-tolerance
Product Name | NanoGel™-50Q HC | NanoGel™-50Q | NanoGel™-50SP | NanoGel™-50SP HP |
Chromatography Technique | Strong anion | Strong anion | Strong cation | Strong cation |
Matrix | PS/DVB | PS/DVB | PS/DVB | PS/DVB |
Particle Size | 50 μm | 50 μm | 50 μm | 50 μm |
Ligand | Quaternary ammonium | Quaternary ammonium | Sulfonate | Sulfonate |
Ligand Density | ~0.25 meq·mL-1 | ~0.20 meq·mL-1 | ~0.16 meq·mL-1 | ~0.14 meq·mL-1 |
Dynamic Binding Capacity | ~120 mg·mL-1（BSA） | ~80 mg·mL-1（BSA） | ~100 mg·mL-1（Lys） | ~70 mg·mL-1（hIgG） |
Maximum Pressure | 2.0 MPa | 2.0 MPa | 2.0 MPa | 2.0 MPa |
Clean In Place | 1 M NaOH | 1 M NaOH | 1 M NaOH | 1 M NaOH |
Recommended Flow Velocity | 300-1200 cm/h | |||
pH Stability | 1-14 | |||
Chemical Stability | Stable in commonly used buffers, 1 M HAc, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropyl alcohol, 30% acetonitrile,1% SDS, 6 M guanidine hydrochloride, 8 M urea, etc. Avoid long-term exposure to strong oxidant. Do not be exposed to strong oxidants (such as hypochlorite), oxidizing acids (such as nitric acid), strong reducing agents (such as sulfites), acetone, or benzyl alcohol. | |||
Operational Temperature | 4-30 ℃ | |||
Storage | 20% Ethanol, 4-25 ℃ | |||
Product Name | Pack Size | Cat. No. |
NanoGel-50SP 10mL | 10mL | 04062-050200-2010 |
NanoGel-50SP 30mL | 30mL | 04062-050200-2030 |
NanoGel-50SP 50mL | 50mL | 04062-050200-2050 |
NanoGel-50SP 100mL | 100mL | 04062-050200-2100 |
NanoGel-50SP 300mL | 300mL | 04062-050200-2300 |
NanoGel-50SP 500mL | 500mL | 04062-050200-2500 |
NanoGel-50SP 1L | 1L | 04062-050200-1001 |
NanoGel-50SP 5L | 5L | 04062-050200-1005 |
NanoGel-50SP 10L | 10L | 04062-050200-1010 |
NanoGel-50SP 50L | 50L | 04062-050200-1050 |
NanoGel-50SP 100L | 100L | 04062-050200-1100 |
NanoGel-50SP HP 10mL | 10mL | 04062-050150-2010 |
NanoGel-50SP HP 30mL | 30mL | 04062-050150-2030 |
NanoGel-50SP HP 50mL | 50mL | 04062-050150-2050 |
NanoGel-50SP HP 100mL | 100mL | 04062-050150-2100 |
NanoGel-50SP HP 300mL | 300mL | 04062-050150-2300 |
NanoGel-50SP HP 500mL | 500mL | 04062-050150-2500 |
NanoGel-50SP HP 1L | 1L | 04062-050150-1001 |
NanoGel-50SP HP 5L | 5L | 04062-050150-1005 |
NanoGel-50SP HP 10L | 10L | 04062-050150-1010 |
NanoGel-50SP HP 50L | 50L | 04062-050150-1050 |
NanoGel-50SP HP 100L | 100L | 04062-050150-1100 |
NanoGel-50Q 10mL | 10mL | 04064-050200-2010 |
NanoGel-50Q 30mL | 30mL | 04064-050200-2030 |
NanoGel-50Q 50mL | 50mL | 04064-050200-2050 |
NanoGel-50Q 100mL | 100mL | 04064-050200-2100 |
NanoGel-50Q 300mL | 300mL | 04064-050200-2300 |
NanoGel-50Q 500mL | 500mL | 04064-050200-2500 |
NanoGel-50Q 1L | 1L | 04064-050200-1001 |
NanoGel-50Q 5L | 5L | 04064-050200-1005 |
NanoGel-50Q 10L | 10L | 04064-050200-1010 |
NanoGel-50Q 50L | 50L | 04064-050200-1050 |
NanoGel-50Q 100L | 100L | 04064-050200-1100 |
NanoGel-50Q HC 10mL | 10mL | 04064-050150-2010 |
NanoGel-50Q HC 30mL | 30mL | 04064-050150-2030 |
NanoGel-50Q HC 50mL | 50mL | 04064-050150-2050 |
NanoGel-50Q HC 100mL | 100mL | 04064-050150-2100 |
NanoGel-50Q HC 300mL | 300mL | 04064-050150-2300 |
NanoGel-50Q HC 500mL | 500mL | 04064-050150-2500 |
NanoGel-50Q HC 1L | 1L | 04064-050150-1001 |
NanoGel-50Q HC 5L | 5L | 04064-050150-1005 |
NanoGel-50Q HC 10L | 10L | 04064-050150-1010 |
NanoGel-50Q HC 50L | 50L | 04064-050150-1050 |
NanoGel-50Q HC 100L | 100L | 04064-050150-1100 |
Address：400 W Cummings Park, Suite 5000, Woburn, MA 01801
Phone: +1-(508) 338-3051
Address：1033, Tower A, Ithum Building, plot-A40 Noida Sector 62, Gsutam Buddha Nagar Uttar Pradesh 201301, INDIA
Phone: +91 96548 80558
Address：No. 2, Baichuan street, Suzhou Industrial Park
Phone：400-828-1622
