Nano series IEX resins are designed for the application of high resolution polishing chromatography. They are made from monodisperse PS-DVB matrix of smaller particle sizes (10µm, 15µm and 30µm) . The surface of the matrix is bonded with a hydrophilic layer, which minimizes the non-specific adsorption of biomolecules by the matrix. Nano series IEX resins have demonstrated superior resolution performance, and they are mainly used for high resolution polishing. For example, NanoQ-30L and NanoQ-15L are widely applied in oligonucleotide AEX chromatography purification, and NanoSP 15L and NanoSP 30L are popular CEX chromatography resins for insulin and peptide purification.
High resolution
Highly rigid matrix enabling high flow rate operation
Very high chemical and physical stability
Nano series ion exchange resins include NanoQ-10L / NanoSP-10L / NanoQ-15L / NanoSP-15L / NanoQ-30L / NanoSP-30L.
Product Name | NanoSP®-10L | NanoQ-10L | NanoSP®-15L | NanoQ-15L | NanoSP®-30L | NanoQ-30L |
Chromatography technique | Strong cation | Strong anion | Strong cation | Strong anion | Strong cation | Strong anion |
Matrix | PS/DVB | PS/DVB | PS/DVB | PS/DVB | PS/DVB | PS/DVB |
Particle Size | 10 µm | 10 µm | 15 µm | 15 µm | 30 µm | 30 µm |
Ligand | Sulfonate | Quaternary ammonium | Sulfonate | Quaternary ammonium | Sulfonate | Quaternary ammonium |
Ligand Density | ~0.27 meq·mL-1 | ~0.28 meq·mL-1 | ~0.26 meq·mL-1 | ~0.27 meq·mL-1 | ~0.19 meq·mL-1 | ~0.21 meq·mL-1 |
Dynamic Binding Capacity | ~80 mg·mL-1 (Lys) | ~65 mg·mL-1 (BSA) | ~ 80 mg·mL-1 (Lys) | ~55 mg·mL-1 (BSA) | ~ 60 mg·mL-1 (Lys) | ~45 mg·mL-1 (BSA) |
Maximum Pressure | 8 MPa | 8 MPa | 6 MPa | 6 MPa | 2 MPa | 2 MPa |
Clean In Place | 1 M NaOH | 0.5 M NaOH | 1 M NaOH | 0.5 M NaOH | 1 M NaOH | 0.5 M NaOH |
Recommended Flow Velocity | 100-750 cm/h | 100-750 cm/h | 150-800 cm/h | 150-800 cm/h | 250-1000 cm/h | 250-1000 cm/h |
pH Stability | 2-12 | 2-12 | 2-12 | 2-12 | 2-12 | 2-12 |
Chemical Stability | Stable in commonly used buffers, 1 M HAc, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropyl alcohol, 30% acetonitrile,1% SDS, 6 M guanidine hydrochloride, 8 M urea, etc. Avoid long-term exposure to strong oxidant. | |||||
Operational Temperature | 4-30 ℃ | |||||
Storage | 20% Ethanol, 4-25 ℃ | |||||
Product Name | Pack Size | Cat. No. |
NanoSP-10L 10mL | 10mL | 04042-010100-2010 |
NanoSP-10L 30mL | 30mL | 04042-010100-2030 |
NanoSP-10L 50mL | 50mL | 04042-010100-2050 |
NanoSP-10L 100mL | 100mL | 04042-010100-2100 |
NanoSP-10L 300mL | 300mL | 04042-010100-2300 |
NanoSP-10L 500mL | 500mL | 04042-010100-2500 |
NanoSP-10L 1L | 1L | 04042-010100-1001 |
NanoSP-10L 5L | 5L | 04042-010100-1005 |
NanoSP-10L 10L | 10L | 04042-010100-1010 |
NanoSP-10L 50L | 50L | 04042-010100-1050 |
NanoSP-10L 100L | 100L | 04042-010100-1100 |
NanoQ-10L 10mL | 10mL | 04044-010100-2010 |
NanoQ-10L 30mL | 30mL | 04044-010100-2030 |
NanoQ-10L 50mL | 50mL | 04044-010100-2050 |
NanoQ-10L 100mL | 100mL | 04044-010100-2100 |
NanoQ-10L 300mL | 300mL | 04044-010100-2300 |
NanoQ-10L 500mL | 500mL | 04044-010100-2500 |
NanoQ-10L 1L | 1L | 04044-010100-1001 |
NanoQ-10L 5L | 5L | 04044-010100-1005 |
NanoQ-10L 10L | 10L | 04044-010100-1010 |
NanoQ-10L 50L | 50L | 04044-010100-1050 |
NanoQ-10L 100L | 100L | 04044-010100-1100 |
NanoSP-15L 10mL | 10mL | 04042-015100-2010 |
NanoSP-15L 30mL | 30mL | 04042-015100-2030 |
NanoSP-15L 50mL | 50mL | 04042-015100-2050 |
NanoSP-15L 100mL | 100mL | 04042-015100-2100 |
NanoSP-15L 300mL | 300mL | 04042-015100-2300 |
NanoSP-15L 500mL | 500mL | 04042-015100-2500 |
NanoSP-15L 1L | 1L | 04042-015100-1001 |
NanoSP-15L 5L | 5L | 04042-015100-1005 |
NanoSP-15L 10L | 10L | 04042-015100-1010 |
NanoSP-15L 50L | 50L | 04042-015100-1050 |
NanoSP-15L 100L | 100L | 04042-015100-1100 |
NanoQ-15L 10mL | 10mL | 04044-015100-2010 |
NanoQ-15L 30mL | 30mL | 04044-015100-2030 |
NanoQ-15L 50mL | 50mL | 04044-015100-2050 |
NanoQ-15L 100mL | 100mL | 04044-015100-2100 |
NanoQ-15L 300mL | 300mL | 04044-015100-2300 |
NanoQ-15L 500mL | 500mL | 04044-015100-2500 |
NanoQ-15L 1L | 1L | 04044-015100-1001 |
NanoQ-15L 5L | 5L | 04044-015100-1005 |
NanoQ-15L 10L | 10L | 04044-015100-1010 |
NanoQ-15L 50L | 50L | 04044-015100-1050 |
NanoQ-15L 100L | 100L | 04044-015100-1100 |
NanoSP-30L 10mL | 10mL | 04042-030100-2010 |
NanoSP-30L 30mL | 30mL | 04042-030100-2030 |
NanoSP-30L 50mL | 50mL | 04042-030100-2050 |
NanoSP-30L 100mL | 100mL | 04042-030100-2100 |
NanoSP-30L 300mL | 300mL | 04042-030100-2300 |
NanoSP-30L 500mL | 500mL | 04042-030100-2500 |
NanoSP-30L 1L | 1L | 04042-030100-1001 |
NanoSP-30L 5L | 5L | 04042-030100-1005 |
NanoSP-30L 10L | 10L | 04042-030100-1010 |
NanoSP-30L 50L | 50L | 04042-030100-1050 |
NanoSP-30L 100L | 100L | 04042-030100-1100 |
NanoQ-30L 10mL | 10mL | 04044-030100-2010 |
NanoQ-30L 30mL | 30mL | 04044-030100-2030 |
NanoQ-30L 50mL | 50mL | 04044-030100-2050 |
NanoQ-30L 100mL | 100mL | 04044-030100-2100 |
NanoQ-30L 300mL | 300mL | 04044-030100-2300 |
NanoQ-30L 500mL | 500mL | 04044-030100-2500 |
NanoQ-30L 1L | 1L | 04044-030100-1001 |
NanoQ-30L 5L | 5L | 04044-030100-1005 |
NanoQ-30L 10L | 10L | 04044-030100-1010 |
NanoQ-30L 50L | 50L | 04044-030100-1050 |
NanoQ-30L 100L | 100L | 04044-030100-1100 |
Address：400 W Cummings Park, Suite 5000, Woburn, MA 01801
Phone: +1-(508) 338-3051
Address：1033, Tower A, Ithum Building, plot-A40 Noida Sector 62, Gsutam Buddha Nagar Uttar Pradesh 201301, INDIA
Phone: +91 96548 80558
Address：No. 2, Baichuan street, Suzhou Industrial Park
Phone：400-828-1622
