NanoGel dT20 was designed to address the selectivity and capacity requirements for large-scale downstream purification of a range of mRNA constructs used in vaccine and gene therapy applications. It can selectively captures the mRNA via the polyadenylated (polyA) tail using simple purification steps of salt for binding and water for elution. NanoGel dT20 effectively separates mRNA from components of the transcription reaction process, such as enzymes and plasmid DNA. It allows for a robust platform and efficient purification process for a range of mRNA molecules and applications.

• Monodisperse matrix of very wide pores provides high binding capacity

• Simplified workflow, high efficiency

• Excellent scalability